Animal Defenders International


Animal Defenders International

Declaration for Advanced Science

Posted: 17 April 2019. Updated: 18 July 2019

An initiative spearheaded by Animal Defenders International, signatories to the Declaration for Advanced Science support measures accelerating the “move away from animal models towards more human-relevant research methods”.

Announced at the ADI-sponsored UK launch of the book Animal Experimentation: Working Towards a Paradigm Change we are delighted that nearly 100 academics, scientists, institutions, companies, organisations and celebrities have signed up to the Declaration, the wording of which is as follows, to date. For the full list of signatures see below.

Declaration for Advanced Science
Recognising the need for a move away from animal models towards more human-relevant research methods, with a goal, as described in Recital 10 of EU Directive 2010/63/EU, and policy for ‘full replacement of procedures on live animals for scientific and educational purposes as soon as scientifically possible’, we pledge to support research and legislative measures which accelerate the realisation of this goal, worldwide.

Supporting the Declaration and its aim, Sir Mike Penning MP has tabled Early Day Motion 2228 which calls on the UK Government to become a leader in the development of innovative non-animal science. If you live in the UK, please urge your MP to support.

Latest figures show 3.7 million animals are used in British laboratories, with an additional 1.8 million animals bred and killed because they were only used for breeding, were the “wrong” sex for the experiment, were used just for tissues, or “necessary surplus resulting from the breeding of animals to ensure adequate supply”.

In the US, although more than 792,000 are officially used, this figure excludes mice and rats, estimated to account for 95% of all experiments and tens of millions of animals. Worldwide, an estimated 115+ million animals are used for scientific purposes.

Due to species differences, animals respond differently to substances such as drugs, and are therefore an unreliable way to predict effects in humans. Not naturally occurring, human diseases in laboratory animals need to be artificially created and are therefore different from the human condition they attempt to mimic. It should not be surprising therefore that more than 90% of drugs that prove promising in animal trials fail in human trials, either due to lack of effectiveness, or safety concerns, and that around 50% of drugs being taken by the wider public are later withdrawn from the market.

Instead of these misleading animal tests, ADI urges governments and regulators to drive research towards modern methods – better for animals and people.

How you can help

  • In the UK, ask your MP to sign Early Day Motion #2228: Developing Innovative Science – Better for Animals TODAY. Our template letter for this can be found here
  • In the US, ask your Representatives to support measures accelerating the move away from animal models towards more human-relevant research.
  • Make a donation to support our work to help animals in laboratories.

Declaration signatories

  • Professor Alberto Alemanno, Professor of EU Law
  • Professor Marc Bekoff, Professor Emeritus of Ecology and Evolutionary Biology
  • Professor Paul Furlong, Professor of Clinical Neuroimaging
  • Professor Robert Garner, Professor of Politics
  • Professor Stevan Harnad, Cognitive Scientist
  • Professor Barbara King, Emerita Professor of Anthropology
  • Professor Andrew Knight, Professor of Animal Welfare and Ethics and Founding Director of the Centre for Animal Welfare
  • Professor Claus Leitzmann, Professor of Nutrition, University Giessen, Germany
  • Professor Corine Pelluchon, Professor of Philosophy, University of Paris-Est-Marne-la-Vallée
  • Professor Laura Waters, Professor of Pharmaceutical Analysis
  • Dr Aysha Akhtar, Medical Doctor specialising in Neurology and Public Health
  • Dr Jonathan Balcombe, Doctor of Ethology
  • Dr Luciana Baroni, Doctor and President of Scientific Society for Vegetarian Nutrition (Società Scientifica di Nutrizione Vegetariana, Italy
  • Dr Luisa Bastos, Doctor of Biomedical Engineering
  • Dr Charlotte E Blattner, Doctor of Animal Law
  • Dr Vanessa Carli Bones, Veterinarian
  • Dr Natasha Boyland, Doctor of Animal Behaviour
  • Dr Simon Brooman, Senior Lecturer in Animal Law
  • Dr Pelin L Candarlioglu, Doctor of Bone Tissue Engineering and Regenerative Medicine
  • Dr Warren Casey, Doctor of Microbiology
  • Dr Mara-Daria Cojocaru, Doctor of Political Philosophy
  • Dr Areli K Cuevas-Ocampo, Doctor of Medicine, Consultant Neuropathologist
  • Dr Stephen Dunne, Doctor of Medicine, Consultant Neuropathologist
  • Dr Corina Gericke, Doctor of Veterinary Medicine and Vice President of Doctors Against Animal Experiments
  • Dr Trent Grassian, Doctor of Social Policy
  • Dr Justine Hollyer, Doctor of Statistics
  • Dr Kimberley Jayne, Doctor of Animal Behaviour and Senior Science Researcher at Animal Defenders International
  • Dr Melanie Joy, Doctor of Social Psychology and Founder and President of Beyond Carnism
  • Dr Shireen Kassam, Medical Doctor and Consultant Haematologist
  • Dr Lori Marino, Neuroscientist and Executive Director, Kimmela Center for Animal Advocacy
  • Dr Andrew Kelly, Doctor of Biological Sciences and Chief Executive Officer, Irish Society for the Prevention of Cruelty to Animals
  • Dr Monkia Merkes, Doctor of Public Health
  • Dr Christina Nellist, Doctor of Eastern Orthodox Theology
  • Dr Oriano Perata, Doctor of Medicine and General Surgery
  • Dr John J Pippin, Doctor of Medicine and Director of Academic Affairs at the Physicians Committee for Responsible Medicine
  • Dr Pandora Pound, Doctor of Sociology of Medicine and Research Consultant to Safer Medicines Trust
  • Dr Keith Redhead, Doctor of Microbiology
  • Dr Jeff Sebo, Doctor of Philosophy
  • Dr Adam See, Doctor of Philosophy
  • Dr Hannah Short, Doctor of Medicine and Accredited Specialist in Menopause & Premenstrual Disorders
  • Dr Aryan Tavakkoli, Medical Doctor and Specialist in Respiratory Medicine and Functional Medicine
  • Dr Jan Turner, Doctor of Genetic Toxicology and Director of Safer Medicines Trust
  • Dr Richard Twine, Doctor of Philosophy
  • Dr Toni Vernelli, Doctor of Animal Behaviour
  • Dr Arian Wallach, Doctor of Ecology
  • Kathy Archibald, Chair of Trustees at Safer Medicines Trust
  • Marissa Buell, Director of Engineering, Aether 3D Bioprinting
  • Ryan Franks, CEO and Founder of Aether 3D Bioprinting
  • Felicity Gogley, Masters Student in Animal Welfare Science, Ethics & Law
  • Tara Jackson, Executive Director of the New Zealand Anti-Vivisection Society
  • Robyn Kirby, Projects & Administration at Humane Research Australia
  • Helen Marston, Chief Executive of Humane Research Australia
  • Pablo Martinez Pancorb, PhD Researcher in Physics and Engineering, University of Exeter
  • Sam McIntyre, MSc Quality and Safety of Healthcare
  • Melani Nardone, PhD Researcher in Anthrozoology
  • Alice Oven, Masters Student in Animal Welfare Science, Ethics & Law
  • Vivien Pomfrey, MSc in Science
  • Pamela A Popper, President, Wellness Forum Health
  • Rebecca Ram, Clinical Data Management and Scientific Research Consultant
  • Susan Starkey, Non-trustee advisor to Run Free Alliance
  • Cheryl Veitch, Treasurer of Humane Research Australia
  • Christine Wynne, Founder and non-trustee advisor to Run Free Alliance
  • Aether (3D Bioprinters)
  • Animal Defenders International
  • Animal Interfaith Alliance
  • Animal Justice Project
  • Beyond Carnism
  • Centre for Animal Welfare, University of Winchester
  • Doctors Against Animal Experiments
  • Ethical Investors (UK) Ltd
  • Gaia
  • Humane Research Australia
  • Irish Society for the Prevention of Cruelty to Animals
  • Lega Anti Vivisezione (LAV)
  • Lord Dowding Fund
  • National Anti-Vivisection Society
  • New Zealand Anti-Vivisection Society
  • Norwegian Animal Protection Alliance
  • Pan Orthodox Concern for Animals
  • Physicians Committee for Responsible Medicine
  • Quaker Concern for Animals
  • Run Free Alliance
  • Safer Medicines Trust
  • Scientific Society for Vegetarian Nutrition (Società Scientifica di Nutrizione Vegetariana, Italy)
  • Gemma Atkinson
  • Brian Blessed
  • James Cromwell
  • Joanna Lumley
  • Chris Packham
  • Alexei Sayle
  • Jenny Seagrove
  • Mena Suvari
  • Benjamin Zephaniah

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